Bellucci was born in Italy. She is the only child of Luigi Bellucci and Maria Gustinelli. Her father was the owner of a transport company where her mother was a painter.
During 16 Bellucci started modelling for that she was attending the Liceo classico. Initially Bellucci modeled to pay her tuition at the University of Perugia,but the lifestyle tempted her away from her law studies.
She speaks Italian, French, and English fluently, Spanish semi-fluently, and she has had speaking roles in each of these languages as well as in Aramaic for her part as Mary Magdalene in The Passion of the Christ.